产品货号：
Z26342
中文名称：
SH3BP2抗体
英文名称：
Anti-SH3BP2 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SH3BP2 Antibody |
| 指标别名 | SH3BP2 pS427;phosphorylated SH3BP2;SH3 domain-binding protein 2;SH3BP2 Src homology 3 Binding Protein 2;3BP-2;RES4-23;3BP2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | SH3BP2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human 3BP2 protein. |
| 计算分子量 | 62KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | 3BP2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | SH3BP2 Src Homology 3 Binding Protein 2 is also known as 3BP-2 and SH3 Binding Protein 2.The Src homology 3 (SH3) region is a small protein domain presented in a very large group of proteins,including cytoskeletal elements and signaling proteins.SH3 domains are believed to serve as modules that mediate protein-protein associations and,along with Src homology 2 (SH2) domains,regulate cytoplasmic signaling.SH3BP2 is composed of an N terminal pleckstrin homology (PH) domain,a ten aa SH3 binding domain,three modular peptide recognition domains,and a C terminal SH2 domain.SH3BP2 function relates to signal transduction and regulation.SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways.Phosphorylation of SH3BP2 occurs on S427 for activation.SH3BP2 mediates interactions of huntingtin and MLK2 (mixed lineage kinase).Defects in SH3BP2 are the cause of cherubism (CRBM),an autosomal dominant inherited syndrome.It is characterized by excessive bone degradation of the upper and lower jaws,which often begins around three years of age.It is followed by development of fibrous tissue masses,which causes a characteristic facial swelling. |
| Uniprot ID | P78314 |
| 基因名全称 | SH3 domain-binding protein 2 |
| 蛋白名全称 | SH3 domain-binding protein 2 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
相关搜索：SH3BP2抗体，SH3BP2多抗，Anti-SH3BP2 Antibody